Getting XALKORI® (crizotinib)

Getting XALKORI

XALKORI^® (crizotinib) is a prescription medicine that is only available at certain specialty pharmacies that handle medicines not carried by regular neighborhood drugstores. So let's talk about how to get XALKORI with your doctor's prescription, and how you may be able to get financial assistance to help with your co-pay.

Filling your XALKORI prescription

You can only get XALKORI through specialty pharmacies. Your doctor’s office may help you fill your prescription through the specialty pharmacy that is right for you and your insurance.

Once your insurance coverage has been verified, the specialty pharmacy should contact you to set up delivery of your prescription. Typically, the specialty pharmacy will bill your insurance provider for the covered cost of XALKORI and bill you for the remaining co-pay.

For assistance with filling your XALKORI prescription and finding a specialty pharmacy, call a Pfizer First Resource^® Program counselor at 1-877-744-5675.

Filling Your Prescription | Financial Assistance

Financial assistance for XALKORI

Pfizer is committed to helping you get the Pfizer medicine you need.

Co-pay assistance is available for eligible insured patients with a prescription for XALKORI. There are certain financial and other restrictions. Be sure to ask if you qualify. Click here for full terms and conditions.

To learn more, call 1-855-XALKORI (1-855-925-5674) Monday through Friday between 8 am and 8 pm ET. Eligible patients will pay no more than $100 for each prescription refill.

If you are uninsured or fail to qualify for co-pay assistance, your First Resource® counselor can help find programs you may be eligible for to get XALKORI® (crizotinib).

If you are uninsured or don’t have sufficient coverage for XALKORI, call 1-877-744-5675 to talk to a counselor at the Pfizer First Resource® Program. They are available Monday through Friday, 9 am to 8 pm ET and can help verify whether you are eligible for patient assistance.

Co-pay assistance will be accepted only in participating pharmacies.

Filling Your Prescription | Financial Assistance

If your tumor is ALK+, XALKORI may be a treatment option for you. But the only way to know is to take the test.

Indication

XALKORI^® (crizotinib) is a prescription medicine used to treat non-small cell lung cancer (NSCLC) that is advanced or has spread to other parts of the body and is caused by a defect in a gene called ALK (anaplastic lymphoma kinase). XALKORI approval is based on the percentage of patients whose tumors responded to treatment.

It is not known whether XALKORI will improve symptoms or will help patients with this disease live longer. It is not known if XALKORI is safe and effective in children.

Important safety information

XALKORI® (crizotinib) may cause serious side effects, some of which may include:

Liver problems — XALKORI may cause life-threatening and/or fatal liver injury. Your doctor should do blood tests every month to check your liver while you are taking XALKORI. Tell your doctor right away if you get any of the following:

your skin or the whites of your eyes turn yellow
you feel tired
your urine turns dark or brown (tea color)
you have nausea or vomiting
you have a decreased appetite
you have pain on the right side of your stomach
you bleed or bruise more easily than normal
you have itching

Swelling of the lungs (pneumonitis) — XALKORI may cause life-threatening and/or fatal swelling (inflammation) of the lungs during treatment. Symptoms may be similar to those symptoms from lung cancer. Tell your doctor right away if you have any new or worsening symptoms, including:

trouble breathing or shortness of breath
cough with or without mucous
fever

Changes in heartbeat (called QT interval prolongation), very fast or abnormal heartbeats — Your doctor may check your heart during treatment with XALKORI. Tell your doctor right away if you have abnormal heartbeats, feel dizzy, or faint. These may be symptoms related to QT interval prolongation.

Before you take XALKORI, tell your doctor if you:

have heart problems, including a condition called long QT syndrome
have liver or kidney problems
have any other medical conditions
are pregnant, or plan to become pregnant. XALKORI may harm your unborn baby.
- >Women who are able to become pregnant and men who take XALKORI should use birth control during treatment and for 3 months after stopping XALKORI.
- >Talk to your doctor about the birth control methods that may be right for you.
- >If you or your partner becomes pregnant, tell your doctor right away.
are breastfeeding or plan to breastfeed. It is not known if XALKORI® (crizotinib) passes into your breast milk. You and your doctor should decide if you will take XALKORI or breastfeed. You should not do both.

Especially tell your doctor if you take:

St. John’s Wort (Hypericum perforatum)
medicines for:
- >depression (antidepressants)
- >fungal infections (antifungals)
- >bacterial infections (antibiotics)
- >tuberculosis (TB)
- >HIV-AIDS
- >heart conditions
- >seizures

Know the medicines you take. Keep a list of them to show your doctor or pharmacist when you get a new medicine.

Do not drink grapefruit juice or eat grapefruit during treatment with XALKORI. It may increase the amount of XALKORI in your blood to a harmful level.

The most common side effects of XALKORI include:

vision problems — these problems usually happen within 2 weeks of starting XALKORI. Tell your doctor right away if you have any change in vision, such as:
- >flashes of light
- >blurred vision
- >light hurting your eyes
- >new or increased floaters
nausea
diarrhea
vomiting
swelling of your hands or feet
constipation

Use caution when driving or operating machinery as XALKORI may cause changes in vision or make you feel tired or dizzy.

These are not all of the possible side effects of XALKORI. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088).

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

Pfizer, PO Box 29387, Mission, KS 66201.

Last Updated: December 2012
CRI512424-01

Indication: XALKORI is a prescription medicine used to treat non-small cell lung cancer (NSCLC) that is advanced or has spread to other parts of the body and is caused by a defect in a gene called ALK (anaplastic lymphoma kinase). XALKORI approval is based on the percentage of patients whose tumors responded to treatment. It is not known whether XALKORI will improve symptoms or will help patients with this disease live longer. It is not known if XALKORI is safe and effective in children.

You are now Leaving xalkori.com

Links to all outside sites are provided as a resource to our visitors. Pfizer accepts no responsibility for the content of sites that are not owned and operated by Pfizer.

The information on the following site is intended for healthcare professionals in the United States and it is not intended for the general public.

Terms and Conditions for Co-pay Program

By enrolling in the XALKORI^® (crizotinib) co-pay offer, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:

1) The offer is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare, or other federal or state healthcare programs (including any state prescription drug assistance programs and the Government Health Insurance Plan available in Puerto Rico [formerly known as "La Reforma de Salud"]).
2) The offer is not valid for prescriptions that are eligible to be reimbursed by private insurance plans or other health or pharmacy benefit programs that reimburse you for the entire cost of your prescription drugs.
3) You will pay no more than $100 of your co-pay on each prescription for up to a maximum annual savings of $24,000.
4) You must deduct the value received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf.
5) Cannot be combined with any other rebate/coupon, free trial, or similar offer for the specified prescription.
6) The offer will be accepted only at participating pharmacies.
7) This offer is not health insurance.
8) Offer good only in the US and Puerto Rico.
9) Pfizer reserves the right to rescind, revoke, or amend the program without notice.
10) Program expires 12/31 of current year.
11) No membership fees.
12) The offer is limited to 1 per person during this offering period and is not transferable.
13) For customer service inquiries, call 1-888-779-2091. For reimbursement when using a non-participating pharmacy/mail order: Pay for XALKORI prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: XALKORI Co-pay Program, 6501 Weston Parkway, Suite 370, Cary, NC 27513.

Offer is valid per calendar year. Patients will be required to re-enroll at the start of a new year.